Transplanted lungs and the “white plague”

@article{Cassir2017TransplantedLA,
  title={Transplanted lungs and the “white plague”},
  author={Nadim Cassir and Robin Delacroix and Carine Gomez and V{\'e}ronique Secq and Martine Reynaud‐Gaubert and Pascal Alexandre Thomas and Laurent Papazian and Michel Drancourt},
  journal={Medicine},
  year={2017},
  volume={96}
}
Rationale: Solid organ transplant recipients, especially after lung transplantation, are at increased risk for Mycobacterium tuberculosis pulmonary tuberculosis due to lifelong immunosuppression. Patient concerns: A 41-year-old woman underwent a second bilateral lung transplantation that was complicated by fatal pulmonary tuberculosis. Diagnoses: Histological examination of a lung biopsy performed 6 weeks after retransplantation revealed a caseating granuloma and necrosis. Acid-fast bacilli… 
Management and prophylaxis of bacterial and mycobacterial infections among lung transplant recipients.
TLDR
A comprehensive approach that includes pre-transplant evaluation, perioperative prophylaxis, long-term antimicrobial prophYLaxis, immunization, and safer living at home and in the community, should be employed to minimize the risk of infection.
Anatomic and Cellular Niches for Mycobacterium tuberculosis in Latent Tuberculosis Infection
TLDR
Latent tuberculosis has been recognized for over a century, but discovery of new niches, where Mycobacterium tuberculosis resides, continues, highlighting that mesenchymal and hematopoietic stem cells harbor organisms in sensitized asymptomatic individuals.

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