Transplanted Oligodendrocytes and Motoneuron Progenitors Generated from Human Embryonic Stem Cells Promote Locomotor Recovery After Spinal Cord Transection

@inproceedings{Erceg2010TransplantedOA,
  title={Transplanted Oligodendrocytes and Motoneuron Progenitors Generated from Human Embryonic Stem Cells Promote Locomotor Recovery After Spinal Cord Transection},
  author={Slaven Erceg and Mohammad Ronaghi and Marc Oria and Mireia Garc{\'i}a Rosell{\'o} and Maria Amparo P{\'e}rez Arag{\'o} and Mar{\'i}a Eugenia L{\'o}pez and Ivana Radojevi{\'c} and Victoria Moreno-Manzano and Francisco-Javier Rodr{\'i}guez-Jim{\'e}nez and Shom Shanker Bhattacharya and J. M. Mass{\'o} C{\'o}rdoba and Miodrag Stojkovi{\'c}},
  booktitle={Stem cells},
  year={2010}
}
Human embryonic stem cells (hESC) hold great promise for the treatment of patients with many neurodegenerative diseases particularly those arising from cell loss or neural dysfunction including spinal cord injury. This study evaluates the therapeutic effects of transplanted hESC-derived oligodendrocyte progenitors (OPC) and/or motoneuron progenitors (MP) on axonal remyelination and functional recovery of adult rats after complete spinal cord transection. OPC and/or MP were grafted into the site… CONTINUE READING

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