Transplantation tolerance—where do we stand?

  title={Transplantation tolerance—where do we stand?},
  author={Herman Waldmann},
  journal={Nature Medicine},
Our understanding of tolerance mechanisms has progressed to the point that tolerance-induction protocols are being tested in humans for organ transplantation. However, a range of scientific, ethical, logistic and commercial issues have arisen, and must be resolved before tolerance induction for human allograft patients can become a reality. 

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