Transplantation of olfactory mucosa minimizes axonal branching and promotes the recovery of vibrissae motor performance after facial nerve repair in rats.

@article{GuntinasLichius2002TransplantationOO,
  title={Transplantation of olfactory mucosa minimizes axonal branching and promotes the recovery of vibrissae motor performance after facial nerve repair in rats.},
  author={Orlando Guntinas-Lichius and Konstantin Wewetzer and Toma L. Tomov and Natalie Azzolin and Shohreh Kazemi and M. Streppel and Wolfrum F Neiss and Doychin N Angelov},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2002},
  volume={22 16},
  pages={
          7121-31
        }
}
The occurrence of abnormally associated movements is inevitable after facial nerve transection. The reason for this post-paralytic syndrome is poor guidance of regrowing axons, whereby a given muscle group is reinnervated by misrouted axonal branches. Olfactory ensheathing glia have been shown to reduce axonal sprouting and stimulate axonal regeneration after transplantation into the spinal cord. In the present study, we asked whether transplantation of olfactory mucosa (OM) would also reduce… CONTINUE READING

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