Transplantation of neural stem cells modulates apolipoprotein E expression in a rat model of stroke

@article{Modo2003TransplantationON,
  title={Transplantation of neural stem cells modulates apolipoprotein E expression in a rat model of stroke},
  author={Michel Modo and Kathryn Hopkins and David J. Virley and Helen Hodges},
  journal={Experimental Neurology},
  year={2003},
  volume={183},
  pages={320-329}
}
The expression of apolipoprotein E (apoE) after ischemic brain damage has been associated with plasticity involved in promoting functional recovery. We therefore examined the expression and distribution of apoE in rats that received intraparenchymal grafts of the conditionally immortal stem cell line MHP36 either ipsilateral or contralateral to the lesion or intraventricular grafts 4 months after transplantation. ApoE immunoreactivity was highly expressed in the striatum, somatosensory cortex… CONTINUE READING

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