Transplantation of micro- and macroencapsulated piglet islets into mice and monkeys.

@article{Elliott2005TransplantationOM,
  title={Transplantation of micro- and macroencapsulated piglet islets into mice and monkeys.},
  author={Robert B. Elliott and Livia Escobar and Riccardo Calafiore and Giuseppe Basta and Olga Garkavenko and Alfred V Vasconcellos and Clare Bambra},
  journal={Transplantation proceedings},
  year={2005},
  volume={37 1},
  pages={466-9}
}
Neonatal porcine islets within alginate microcapsules transplanted intraperitoneally (IP) or within semi-permeable macrocapsules (TheraCyte) and transplanted subcutaneously (SC) survive and reverse diabetes for up to 16 weeks in diabetic autoimmune nonobese diabetic (NOD) mice. The islets in microcapsules transplanted IP into nondiabetic cynomolgus monkeys survived for 8 weeks. Similar results were shown with islets transplanted in TheraCytes. Neither species showed adverse effects or evidence… CONTINUE READING

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