Transplantation of mesenchymal stem cells from young donors delays aging in mice

  title={Transplantation of mesenchymal stem cells from young donors delays aging in mice},
  author={Jinhui Shen and Yi-Ting Tsai and Nancy M Dimarco and Michael A. Long and Xiankai Sun and Liping Tang},
  booktitle={Scientific reports},
Increasing evidence suggests that the loss of functional stem cells may be important in the aging process. Our experiments were originally aimed at testing the idea that, in the specific case of age-related osteoporosis, declining function of osteogenic precursor cells might be at least partially responsible. To test this, aging female mice were transplanted with mesenchymal stem cells from aged or young male donors. We find that transplantation of young mesenchymal stem cells significantly… CONTINUE READING
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The author declares no competing financial interests

D. Miao, Scutt, +15 authors L. T. prepared the manuscript. L.T. supervised the pr interests
License: This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. To view a copy of this license, visit How to cite this article: Shen, J., Tsai, Y., DiMarco, N., Sun, X. & Tang, L. Transplantation of • 2011

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