Transplantation of mesenchymal stem cells, recombinant human BMP-2,and their combination in accelerating the union after osteotomy and increasing, the mechanical strength of extracorporeally irradiated femoral autograft in rat models

@inproceedings{Kamal2014TransplantationOM,
  title={Transplantation of mesenchymal stem cells, recombinant human BMP-2,and their combination in accelerating the union after osteotomy and increasing, the mechanical strength of extracorporeally irradiated femoral autograft in rat models},
  author={Achmad Fauzi Kamal and Ismail Hadisoebroto Dilogo and Errol Untung Hutagalung and Diah Iskandriati and Raden Susworo and Nurjati Chaerani Siregar and Achmad Aulia Yusuf and Adang Bachtiar},
  booktitle={Medical journal of the Islamic Republic of Iran},
  year={2014}
}
BACKGROUND Delayed union, nonunion, and mechanical failure is still problems encountered in limb salvage surgery (LSS) using extracorporeal irradiation (ECI). This study aimed to determine whether bone marrow mesenchymal stem cells (MSC) and recombinant human bone morphogenetic protein-2 (rhBMP-2) improve hostgraft union after osteotomy and also increase its mechanical strength. METHODS Thirty Sprague Dawley rats were randomly divided into five groups. Group I (control) underwent LSS using… CONTINUE READING