Transplantation of human umbilical cord blood cells improves glycemia and glomerular hypertrophy in type 2 diabetic mice.

@article{Ende2004TransplantationOH,
  title={Transplantation of human umbilical cord blood cells improves glycemia and glomerular hypertrophy in type 2 diabetic mice.},
  author={Norman Ende and Ruifeng Chen and A. Subbarami Reddi},
  journal={Biochemical and biophysical research communications},
  year={2004},
  volume={321 1},
  pages={168-71}
}
Recent in vitro and in vivo studies have shown that either animal- or human-derived embryonic stem cells can differentiate into insulin-secreting cells and lower blood glucose levels. However, studies utilizing human umbilical cord blood (HUCB) mononuclear cells to improve blood glucose levels in diabetic animals have received little attention. In this study, we examined the effect of transplanted HUCB mononuclear cells on blood glucose levels, survival, and renal pathology in obese mice with… CONTINUE READING

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