Transplantation of human neural stem cells for spinal cord injury in primates.

  title={Transplantation of human neural stem cells for spinal cord injury in primates.},
  author={Akira Iwanami and Shuji Kaneko and Masaya Nakamura and Yonehiro Kanemura and Hiroshi Mori and Saori Kobayashi and Mami Yamasaki and Suketaka Momoshima and Hisayoshi Ishii and Kei Ando and Yoshikuni Tanioka and Norikazu Tamaoki and Tatsuji Nomura and Yoshiaki Toyama and Hideyuki Okano},
  journal={Journal of neuroscience research},
  volume={80 2},
Recent studies have shown that delayed transplantation of neural stem/progenitor cells (NSPCs) into the injured spinal cord can promote functional recovery in adult rats. Preclinical studies using nonhuman primates, however, are necessary before NSPCs can be used in clinical trials to treat human patients with spinal cord injury (SCI). Cervical contusion SCIs were induced in 10 adult common marmosets using a stereotaxic device. Nine days after injury, in vitro-expanded human NSPCs were… CONTINUE READING


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Neural stem cell therapy aiming at better functional recovery after spinal cord injury.

Developmental dynamics : an official publication of the American Association of Anatomists • 2018
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