Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration.

@article{Shirai2016TransplantationOH,
  title={Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration.},
  author={Hiroshi Shirai and Michiko Mandai and Keizo Matsushita and Atsushi Kuwahara and Shigenobu Yonemura and Tokushige Nakano and Juthaporn Assawachananont and Tōru Kimura and Koichi Saito and Hiroko Terasaki and Mototsugu Eiraku and Yoshiki Sasai and Masayo Takahashi},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2016},
  volume={113 1},
  pages={E81-90}
}
Retinal transplantation therapy for retinitis pigmentosa is increasingly of interest due to accumulating evidence of transplantation efficacy from animal studies and development of techniques for the differentiation of human embryonic stem cells (hESCs) and induced pluripotent stem cells into retinal tissues or cells. In this study, we aimed to assess the potential clinical utility of hESC-derived retinal tissues (hESC-retina) using newly developed primate models of retinal degeneration to… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 50 extracted citations

Organoid technology for retinal repair.

Developmental biology • 2018
View 6 Excerpts
Highly Influenced

Evidence for a retinal progenitor cell in the postnatal and adult mouse.

Stem cell research • 2017
View 2 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 37 references

Generation of a ciliary margin-like stem cell niche from selforganizing human retinal tissue

A Kuwahara
Nat Commun • 2015
View 4 Excerpts
Highly Influenced

Restoration of visual function by expression of a light-gated mammalian ion channel in retinal ganglion cells or ON-bipolar cells.

Proceedings of the National Academy of Sciences of the United States of America • 2014
View 1 Excerpt

Restoration of retinal structure and function after selective photocoagulation.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2013
View 1 Excerpt

Similar Papers

Loading similar papers…