Transplantation of galectin-1-expressing human neural stem cells into the injured spinal cord of adult common marmosets.

@article{Yamane2010TransplantationOG,
  title={Transplantation of galectin-1-expressing human neural stem cells into the injured spinal cord of adult common marmosets.},
  author={Junichi Yamane and Masaya Nakamura and Akio Iwanami and Masanori Sakaguchi and Hiroyuki Katoh and Masayuki Yamada and Suketaka Momoshima and Sachiyo Miyao and Ken J Ishii and Norikazu Tamaoki and Tatsuji Nomura and Hirotaka James Okano and Yonehiro Kanemura and Yoshiaki Toyama and Hideyuki Okano},
  journal={Journal of neuroscience research},
  year={2010},
  volume={88 7},
  pages={1394-405}
}
Delayed transplantation of neural stem/progenitor cells (NS/PCs) into the injured spinal cord can promote functional recovery in adult rats and monkeys. To enhance the functional recovery after NS/PC transplantation, we focused on galectin-1, a carbohydrate-binding protein with pleiotropic roles in cell growth, differentiation, apoptosis, and neurite outgrowth. Here, to determine the combined therapeutic effect of NS/PC transplantation and galectin-1 on spinal cord injury (SCI), human NS/PCs… CONTINUE READING