Transplantation of fetal dopamine neurons in Parkinson's disease: PET [18F]6-L-fluorodopa studies in two patients with putaminal implants.

Abstract

Two patients with Parkinson's disease who underwent implantation of fetal mesencephalic tissue into the putamen were serially studied using positron emission tomography and [18F]6-L-fluorodopa ([18F]dopa). The uptake of [18F]dopa is related to the functional integrity of the presynaptic dopaminergic system. Preoperative studies revealed a marked decrease in… (More)

Topics

Cite this paper

@article{Sawle1992TransplantationOF, title={Transplantation of fetal dopamine neurons in Parkinson's disease: PET [18F]6-L-fluorodopa studies in two patients with putaminal implants.}, author={Guy V Sawle and P. M. Bloomfield and Anders Bj{\"{o}rklund and David J. Brooks and Patrik Brundin and Klaus Leonard Leenders and Olle Lindvall and Chris Marsden and Stig Rehncrona and H{\aa}kan Widner}, journal={Annals of neurology}, year={1992}, volume={31 2}, pages={166-73} }