Transplantation of endothelial progenitor cells accelerates dermal wound healing with increased recruitment of monocytes/macrophages and neovascularization.

@article{Suh2005TransplantationOE,
  title={Transplantation of endothelial progenitor cells accelerates dermal wound healing with increased recruitment of monocytes/macrophages and neovascularization.},
  author={Wonhee Suh and Koung Li Kim and Jeong-Min Kim and In-Soon Shin and Young-Sam Lee and Jae-young Lee and Hyung-suk Jang and Jung-Sun Lee and Jonghoe Byun and Jin Ho Choi and E J Jeon and Duk-Kyung Kim},
  journal={Stem cells},
  year={2005},
  volume={23 10},
  pages={1571-8}
}
Endothelial progenitor cells (EPCs) act as endothelial precursors that promote new blood vessel formation and increase angiogenesis by secreting growth factors and cytokines in ischemic tissues. These facts prompt the hypothesis that EPC transplantation should accelerate the wound-repair process by facilitating neovascularization and the production of various molecules related to wound healing. In a murine dermal excisional wound model, EPC transplantation accelerated wound re-epithelialization… CONTINUE READING

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