Transplantation of adipose stromal cells, but not mature adipocytes, augments ischemia-induced angiogenesis.

@article{Sumi2007TransplantationOA,
  title={Transplantation of adipose stromal cells, but not mature adipocytes, augments ischemia-induced angiogenesis.},
  author={Makoto Sumi and Masataka Sata and Naoki Toya and Katsuhiko Yanaga and Takao Ohki and Ryozo Nagai},
  journal={Life sciences},
  year={2007},
  volume={80 6},
  pages={559-65}
}
Therapeutic angiogenesis has emerged as a promising therapy to treat patients with ischemic diseases. Transplantation of bone marrow cells (BMCs) is reported to augment collateral development in ischemic organs either by differentiating into vascular cells or by secreting angiogenic cytokines. Recent evidence suggests that adipose tissues secrete a number of humoral factors and contain pluripotent stem cells. Here, we evaluated the therapeutic potential of adipose tissue-derived cells to… CONTINUE READING

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