Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI)

@inproceedings{Assmus2002TransplantationOP,
  title={Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI)},
  author={Birgit Assmus and Volker Schaechinger and Claudius Teupe and Martina B. Britten and Ralf Lehmann and Natascha Doebert and Frank Gr{\"u}nwald and Alexandra Aicher and Carmen Urbich and Hans C. Martin and Dieter Hoelzer and Stefanie Dimmeler and Andreas Michael Zeiher},
  year={2002}
}
Background— Experimental studies suggest that transplantation of blood-derived or bone marrow–derived progenitor cells beneficially affects postinfarction remodeling. The safety and feasibility of autologous progenitor cell transplantation in patients with ischemic heart disease is unknown. Methods and Results— We randomly allocated 20 patients with reperfused acute myocardial infarction (AMI) to receive intracoronary infusion of either bone marrow–derived (n=9) or circulating blood–derived… CONTINUE READING

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