Transplantation of Induced Pluripotent Stem Cells Alleviates Cerebral Inflammation and Neural Damage in Hemorrhagic Stroke

@inproceedings{Qin2015TransplantationOI,
  title={Transplantation of Induced Pluripotent Stem Cells Alleviates Cerebral Inflammation and Neural Damage in Hemorrhagic Stroke},
  author={Jie Qin and Xun Ming Ma and Haiyun Qi and Bo Song and Yanlin Wang and Xuejun Wen and Qing Mei Wang and Shilei Sun and Yusheng Li and Rui Zhang and Xinjing Liu and Haiman Hou and Guangming Gong and Yuming Xu and Thiruma Valavan Arumugam},
  booktitle={PloS one},
  year={2015}
}
BACKGROUND Little is known about the effects of induced pluripotent stem cell (iPSC) treatment on acute cerebral inflammation and injuries after intracerebral hemorrhage (ICH), though they have shown promising therapeutic potentials in ischemic stoke. METHODS An ICH model was established by stereotactic injection of collagenase VII into the left striatum of male Sprague-Dawley (SD) rats. Six hours later, ICH rats were randomly divided into two groups and received intracerebrally 10 μl of PBS… CONTINUE READING
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