Transplantation of Cbfa1-overexpressing adipose stem cells together with vascularized periosteal flaps repair segmental bone defects.

@article{Li2012TransplantationOC,
  title={Transplantation of Cbfa1-overexpressing adipose stem cells together with vascularized periosteal flaps repair segmental bone defects.},
  author={Jianjun Li and Qun Zhao and Enbo Wang and Chuanhui Zhang and Guangbin Wang and Quan Yuan},
  journal={The Journal of surgical research},
  year={2012},
  volume={176 1},
  pages={e13-20}
}
BACKGROUND Segmental bone defect is still a challenge to orthopedic surgeons. Currently available therapies for segmental bone defects have some drawbacks. Tissue engineering using pluripotent stem cells is a new, promising method for bone repair. The present study aims to promote the effect of bone defect repair using the tissue engineered bone in combination with vascularized periosteal flaps. METHODS The adenoviral vector carrying Cbfa1 transduced rabbit adipose-derived mesenchymal stem… CONTINUE READING
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