Corpus ID: 32301727

Transplantation of Bioprinted Tissues and Organs nges and Future Perspectives Technical and Clinical Challe

@inproceedings{Ravnic2017TransplantationOB,
  title={Transplantation of Bioprinted Tissues and Organs nges and Future Perspectives Technical and Clinical Challe},
  author={Dino J. Ravnic and Ashley N Leberfinger and Srinivas V. Koduru and Monika Hospodiuk and Kazim K. Moncal and Pallab Datta and Madhuri Dey and Elias B Rizk and Ibrahim T. Ozbolat},
  year={2017}
}
Three-dimensional (3D) bioprinting is a revolutionary technology in building living tissues and organs with precise anatomic control and cellular composition. Despite the great progress in bioprinting research, there has yet to be any clinical translation due to current limitations in building human-scale constructs, which are vascularized and readily implantable. In this article, we review the current limitations and challenges in 3D bioprinting, including in situ techniques, which are one of… Expand

Figures and Tables from this paper

Alginate Formulations: Current Developments in the Race for Hydrogel-Based Cardiac Regeneration
TLDR
The focus of this review is to elucidate the promising properties of alginate and to highlight its benefits in clinical trials in relation to cardiac regeneration, examining in depth the ongoing developments to refine the material relevance in cardiac recovery and regeneration after MI. Expand
Disclosing Main authors and Organisations collaborations in bioprinting through network maps analysis
TLDR
A scientometric analysis on bioprinting based on a competitive technology intelligence (CTI) cycle assesses scientific documents to establish the publication rate of science and technology in terms of institutions, patents or journals offers valuable information for the identification of potential associations for biop printing researches and stakeholders. Expand
Can Pension Funds Partially Manage Longevity Risk by Investing in a Longevity Megafund
Pension funds that handle retirement risk need to invest assets in a diversified manner, on long durations and if possible while facing interest rate and longevity risk. In the recent years, a newExpand

References

SHOWING 1-10 OF 78 REFERENCES
3D bioprinting of tissues and organs
TLDR
3D bioprinting is being applied to regenerative medicine to address the need for tissues and organs suitable for transplantation and developing high-throughput 3D-bioprinted tissue models for research, drug discovery and toxicology. Expand
Bioprinting scale-up tissue and organ constructs for transplantation.
TLDR
In this Opinion, possibilities for the bioprinting scale-up of functional tissue and organ constructs for transplantation are highlighted and alternative approaches, their limitations, and promising directions for new research prospects are provided. Expand
A Hybrid Bioprinting Approach for Scale-Up Tissue Fabrication
TLDR
A framework concept for bioprinting 3D large-scale tissues with a perfusable vascular system in vitro to preserve cell viability and tissue maturation is presented and its promising application for in vitro tissue engineering and its potential for therapeutic purposes is envisioned. Expand
Bioprinting Technology: A Current State-of-the-Art Review
Bioprinting is an emerging technology for constructing and fabricating artificial tissue and organ constructs. This technology surpasses the traditional scaffold fabrication approach in tissueExpand
A 3D bioprinting system to produce human-scale tissue constructs with structural integrity
TLDR
An integrated tissue–organ printer (ITOP) that can fabricate stable, human-scale tissue constructs of any shape is presented and the incorporation of microchannels into the tissue constructs facilitates diffusion of nutrients to printed cells, thereby overcoming the diffusion limit of 100–200 μm for cell survival in engineered tissues. Expand
Current advances and future perspectives in extrusion-based bioprinting.
TLDR
This paper, presenting a first-time comprehensive review of EBB, discusses the current advancements in EBB technology and highlights future directions to transform the technology to generate viable end products for tissue engineering and regenerative medicine. Expand
Characterization of printable cellular micro-fluidic channels for tissue engineering.
TLDR
A new approach to the fabrication of vessel-like microfluidic channels that has the potential to be used in thick tissue or organ fabrication in the future and shows that cartilage progenitor cells (CPCs) maintained their viability right after bioprinting and during prolonged in vitro culture. Expand
Scaffold-free vascular tissue engineering using bioprinting.
TLDR
A fully biological self-assembly approach, which is implemented through a rapid prototyping bioprinting method for scaffold-free small diameter vascular reconstruction and has the ability to engineer vessels of distinct shapes and hierarchical trees that combine tubes of distinct diameters. Expand
Tissue engineered vascular grafts: Origins, development, and current strategies for clinical application.
TLDR
The recent development of completely tissue engineered vascular conduits that can be implanted for clinical application and have the potential to supplant older organic but not truly biologic technologies, which are used currently. Expand
A synergistic approach to the design, fabrication and evaluation of 3D printed micro and nano featured scaffolds for vascularized bone tissue repair.
TLDR
This work has successfully designed and printed a series of novel 3D bone scaffolds with both bone formation supporting structures and highly interconnected 3D microvascular mimicking channels, for efficient and enhanced osteogenic bone regeneration as well as vascular cell growth. Expand
...
1
2
3
4
5
...