Transplantation into genetically alymphoid mice as an approach to dissect the roles of uterine natural killer cells during pregnancy--a review.

@article{Croy2000TransplantationIG,
  title={Transplantation into genetically alymphoid mice as an approach to dissect the roles of uterine natural killer cells during pregnancy--a review.},
  author={B Anne Croy and James P Di Santo and Janice D Greenwood and Sirirak Chantakru and Ali A Ashkar},
  journal={Placenta},
  year={2000},
  volume={21 Suppl A},
  pages={S77-80}
}
Mice genetically deficient in the natural killer (NK) cell lineage lack uterine (uNK cells) and demonstrate morphometrically-quantifiable histopathology within their implantation sites. Two particular mouse strains, tg(epsilon),26 and RAG-2 null x gamma(c) null, have been used successfully as transplant recipients to address questions relating to the… CONTINUE READING