Transplantation: IgG reactivity to apoptotic cells—role in presensitization revealed


Presensitization, a long-standing cause of graft failure in solid organ transplantation, is largely attributed to anti-HLA and antiABO antibody-mediated reactions. Now, pretransplant levels of apoptotic-cellreactive IgG have been found to correlate with late kidney allograft loss. “These antibodies have never been associated with presensitization before… (More)
DOI: 10.1038/nrneph.2014.118


  • Presentations referencing similar topics