Transplantation: IgG reactivity to apoptotic cells—role in presensitization revealed

Abstract

Presensitization, a long-standing cause of graft failure in solid organ transplantation, is largely attributed to anti-HLA and antiABO antibody-mediated reactions. Now, pretransplant levels of apoptotic-cellreactive IgG have been found to correlate with late kidney allograft loss. “These antibodies have never been associated with presensitization before… (More)
DOI: 10.1038/nrneph.2014.118

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