Transplantable tumor lines generated in clonal zebrafish.

  title={Transplantable tumor lines generated in clonal zebrafish.},
  author={Igor V Mizgireuv and Sergei Y Revskoy},
  journal={Cancer research},
  volume={66 6},
Transplantable zebrafish tumors are a novel and very promising model in cancer research. However, further progress in this field has been contained by a lack of true inbred lines in zebrafish. To overcome this problem, we generated two lines of homozygous diploid clonal zebrafish lines (i.e., CB1 and CW1), which allowed us to carry out transplantation of any tissue, including tumors, from one fish to another within a line without rejection of the graft. The primary tumors in CB1 fish were… CONTINUE READING