Transplantable choriocarcinoma of rats induced by fetectomy and its biological activities.

@article{Teshima1983TransplantableCO,
  title={Transplantable choriocarcinoma of rats induced by fetectomy and its biological activities.},
  author={Shinichi Teshima and Yukio Shimosato and Tsutomu Koide and Masahide Kuroki and Yasuhiro Kikuchi and Miki Aizawa},
  journal={Gan},
  year={1983},
  volume={74 2},
  pages={205-12}
}
Eight cases of choriocarcinoma were induced in WKA female rats by simple fetectomy without viral inoculation or administration of chemical carcinogens. Among them, one line has been successfully subcutaneously transplanted over 10 generations in syngeneic rats and this line was designated as RCHO. The histological appearance of RCHO consisted of trophoblastic giant cells and small basophilic tumor cells, which resembled normal rat placenta. RCHO possessed marked mammotropic and lactogenic… CONTINUE READING

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