Transplacental transport and tissue distribution of biotin in mice at midgestation.


Biotin is a water-soluble vitamin which functions as a coenzyme of carboxylases in glucose and amino acid metabolism and fatty acid synthesis. Biotin is also essential for maintaining reproductive function. Biotin deficiency during gestation induces cleft palate, micrognathia and limb hypoplasia in mouse fetuses at near term. Maternal biotin deficiency is… (More)
DOI: 10.1111/j.1741-4520.2008.00179.x



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