Transplacental leakage of HBeAg-positive maternal blood as the most likely route in causing intrauterine infection with hepatitis B virus.

@article{Lin1987TransplacentalLO,
  title={Transplacental leakage of HBeAg-positive maternal blood as the most likely route in causing intrauterine infection with hepatitis B virus.},
  author={Ho-Hsiung Lin and T Y Lee and Ding Shinn Chen and Joohon Sung and H Ohto and Takao Etoh and Takashi Kawana and Masahiko Mizuno},
  journal={The Journal of pediatrics},
  year={1987},
  volume={111 6 Pt 1},
  pages={
          877-81
        }
}
Thirty-two HBeAg-positive carrier mothers and their 32 babies were investigated to elucidate the mechanism involved in intrauterine infection with HBV. Five mothers had symptoms and signs of threatened abortion and/or threatened preterm labor. Three mothers gave birth more than 6 weeks after the episodes, and their babies were those infected in utero. The other two gave birth within 1 week after the episodes, and the two babies were treated with HBIG immediately after birth; HBV infection was… CONTINUE READING