Transplacental and milk transfer of polybrominated biphenyls to perinatal guinea pigs from treated dams.

@article{Ecobichon1983TransplacentalAM,
  title={Transplacental and milk transfer of polybrominated biphenyls to perinatal guinea pigs from treated dams.},
  author={Donald J Ecobichon and S Hidvegi and Anne Marie Comeau and Pamela H. Cameron},
  journal={Toxicology},
  year={1983},
  volume={28 1-2},
  pages={51-63}
}
Timed-pregnant albino Hartley strain guinea pigs of approximately 65 days gestation or lactating animals within 6-12 h of parturition received a single oral dose of Firemaster FF-1 (50 mg/kg body wt). The pregnant animals and their fetuses were killed 2 days later at term while the lactating animals and their pups were killed at intervals of 2, 4, 7, 14, 28, 42, and 60 days. Tissues (liver, kidney, lung, perirenal fat) were removed for the analysis of the 2,4,5,2',4',5'-hexabromobiphenyl (HBB… CONTINUE READING

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Toxicological Profile for Polybrominated Biphenyls

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IARC monographs on the evaluation of carcinogenic risks to humans • 2016

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