Transoral robotic surgery and human papillomavirus status: Oncologic results

  title={Transoral robotic surgery and human papillomavirus status: Oncologic results},
  author={Marc A. Cohen and Gregory S. Weinstein and Bert W O'Malley and Michael D. Feldman and Harry Quon},
  journal={Head \& Neck},
Patients with oropharyngeal squamous cell carcinoma (OPSCC) have been shown to have distinct outcome profiles based on their human papillomavirus (HPV) status. The purpose of this study was to assess HPV‐related outcomes after transoral robotic surgery (TORS) with adjuvant therapy as indicated. 

Oncologic outcomes of transoral robotic surgery for HPV‐negative oropharyngeal carcinomas

The TORS approach for resectable HPV-negative OPSCC can achieve encouraging oncologic outcomes with infrequent morbidity.

Transoral robotic surgery for oropharyngeal squamous cell carcinoma in the era of human papillomavirus

This work evaluated the survival by treatment strategy independently in HPV‐related and HPV‐nonrelated oropharyngeal SCC.

Impact of human papillomavirus and smoking on survival outcomes after transoral robotic surgery

Oncologic outcomes of head and neck squamous cell carcinoma treated with transoral robotic surgery (TORS) based on human papillomavirus (HPV) and smoking risk factors are evaluated.

Robotic vs. transoral laser surgery of malignant oropharyngeal tumors—what is best for the patient?

The literature and concepts pertaining to transoral surgery are reviewed and the two most common techniques, transoral laser microsurgery (TLM) and transoral robotic surgery (TORS) are described.

Robotic Surgery for Oropharyngeal Cancer

Transoral robotic surgery (TORS) has opened the door for minimally invasive surgery for HPV-related and non-HPV-related oropharyngeal cancer and has been shown to improve functional outcomes in speech and swallowing, while maintaining good oncologic outcomes.

Adoption of transoral robotic surgery compared with other surgical modalities for treatment of oropharyngeal squamous cell carcinoma

Transoral robotic surgery (TORS) has increased for treatment of oropharyngeal squamous cell carcinoma (OPSCC) in the US and adoption of TORS is defined.

Robotic approaches to the pharynx: tonsil cancer.

Erratum to: Transoral Resection of Human Papillomavirus (HPV)-Positive Squamous Cell Carcinoma of the Oropharynx: Outcomes with and Without Adjuvant Therapy

This study aimed to compare the outcomes for those undergoing transoral resection with or without adjuvant therapy for HPV-related oropharyngeal carcinoma.

HPV‐related oropharyngeal cancer: Risk factors for treatment failure in patients managed with primary transoral robotic surgery

Clinical factors that predict locoregional recurrence or distant metastasis in patients with human papillomavirus‐positive oropharyngeal cancer treated with surgery and guideline‐indicated adjuvant therapy are determined.



Transoral resection of tonsillar squamous cell carcinoma

Oncologic and functional outcomes of patients with tonsillar carcinoma who underwent transoral tumor resection and neck dissection with or without postoperative radiotherapy or chemoradiotherapy are reviewed.

Transoral Robotic Surgery (TORS) for Base of Tongue Neoplasms

Objective: To develop a minimally invasive surgical technique for the treatment of base of tongue neoplasms using the optical and technical advantages of robotic surgical instrumentation.

Prognostic significance of human papillomavirus in oropharyngeal squamous cell carcinomas

Clinical outcomes with HPV status for patients with oropharyngeal carcinomas who were uniformly treated with a concurrent chemoradiation treatment protocol are correlated.

Human papillomavirus positive squamous cell carcinoma of the oropharynx

The authors retrospectively determined the presence of the virus and the integrity of the viral E2 gene in tumors of patients who have undergone curative irradiation of patients with squamous cell carcinoma of the oropharynx.

Transoral robotic surgery: radical tonsillectomy.

Radical tonsillectomy using TORS is a new technique that offers excellent access for resection of carcinomas of the tonsil with acceptable acute morbidity and long-term oncologic and functional outcomes.

Human papillomavirus in laryngeal and hypopharyngeal carcinomas. Relationship to survival.

Laryngeal and hypopharyngea carcinomas with detectable HPV may represent a biologically distinct subset of tumors that carry a poorer prognosis than do cancers with no detectable HPV.

Robot‐Assisted Pharyngeal and Laryngeal Microsurgery: Results of Robotic Cadaver Dissections

This work demonstrates the use of a surgical robot in pharyngeal and microlaryngeAL surgery in a cadaver and suggests that robotic surgery has significant potential in pharyngal andmicrolarynGEal surgery.

Assessment of Intraoperative Safety in Transoral Robotic Surgery

It is hypothesize that these particular risks of transoral surgery are similar with robotic assistance compared with conventional transoral Surgery, and it is hypothesized that these specific risks of Transoral Robotics with daVinci Surgical System are similar.

Transoral lateral oropharyngectomy for squamous cell carcinoma of the tonsillar region: I. Technique, complications, and functional results.

From a functional standpoint, the TLO is a reliable technique that should be considered for treatment of appropriate squamous cell carcinoma of the tonsil and/or tonsillar fossa and its safety, postoperative management, complications, and functional outcomes are described.

Human papillomavirus reduces the prognostic value of nodal involvement in tonsillar squamous cell carcinomas

Assessment of the prognostic value of nodal status in relation to human papillomavirus (HPV) status and the various treatment modalities in tonsillar squamous cell carcinomas (TSCC).