Transoral resection of pharyngeal cancer: Summary of a National Cancer Institute Head and Neck Cancer Steering Committee Clinical Trials Planning Meeting, November 6–7, 2011, Arlington, Virginia

  title={Transoral resection of pharyngeal cancer: Summary of a National Cancer Institute Head and Neck Cancer Steering Committee Clinical Trials Planning Meeting, November 6–7, 2011, Arlington, Virginia},
  author={David J. Adelstein and John Andrew Ridge and David M. Brizel and Floyd Christopher Holsinger and Bruce H. Haughey and Brian O'Sullivan and Eric M Genden and Jonathan J. Beitler and Gregory S. Weinstein and Harry Quon and Douglas B. Chepeha and Robert L Ferris and Randal S Weber and Benjamin Movsas and John N. Waldron and Val J. Lowe and Scott D. Ramsey and Judith B. Manola and Bevan Yueh and Thomas E. Carey and Justin E Bekelman and Andre A. Konski and Eric J Moore and Arlene A. Forastiere and David E. Schuller and Jean Lynn and Claudio Dansky Ullmann},
  journal={Head \& Neck},
Recent advances now permit resection of many pharyngeal tumors through the open mouth, an approach that can greatly reduce the morbidity of surgical exposure. These transoral techniques are being rapidly adopted by the surgical community and hold considerable promise. On November 6–7, 2011, the National Cancer Institute sponsored a Clinical Trials Planning Meeting to address how to further investigate the use of transoral surgery, both in the good prognosis human papillomavirus (HPV)–initiated… 

Transoral Endoscopic Head and Neck Surgery: The Contemporary Treatment of Head and Neck Cancer.

Decision management in transoral robotic surgery: Indications, individual patient selection, and role in the multidisciplinary treatment for head and neck cancer from a European perspective

TORS has become an accepted first‐line treatment for T1 and T2 head and neck squamous cell carcinoma in progressively younger patients and the advantages of TORS over transoral laser microsurgery (TOLM) and open surgery.

Transoral Surgery or Radiotherapy for Oropharyngeal Carcinoma - Is It Either Or…?

  • M. EvansT. Jones
  • Medicine
    Clinical oncology (Royal College of Radiologists (Great Britain))
  • 2016

Adjuvant treatment decisions for oropharyngeal cancer – is it time for a change?

  • T. RackleyN. PalaniappanD. OwensM. Evans
  • Medicine
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
  • 2014
Background for surgical studies investigating whether primary chemoradiotherapy protocols for OPSCC can be modified to reduce toxicity for patients is provided, in particular to consider existing evidence for adjuvant treatment in surgically treated OPSCC.

Swallowing after transoral surgery for oropharyngeal cancer: comparison with primary chemoradiotherapy outcomes

Minimizing swallowing impairment following oropharyngeal squamous cell carcinoma treatment, while ensuring oncological efficacy, should be a priority for head and neck healthcare providers.

Head and neck cancers, Version 2.2014. Clinical practice guidelines in oncology.

This selection from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Head and Neck Cancers focuses on glottic laryngeal cancer, which is the most common type of laryngeal

Transoral Robotic Surgery for Oropharyngeal Carcinoma: Update

Trans-oral robotic surgery appears to be a safe, feasible, and efficacious surgical modality for the treatment of a subset of carefully selected patients with oropharyngeal squamous cell carcinoma, and HPV positive non-smokers appear to particularly benefit.

Transoral Endoscopic Head and Neck Surgery and Its Role Within the Multidisciplinary Treatment Paradigm of Oropharynx Cancer: Robotics, Lasers, and Clinical Trials.

  • F. C. HolsingerR. Ferris
  • Medicine
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 2015
There are no prospective data supporting the use of this new surgical approach for OPC, but the fundamentals of transoral endoscopic head and neck surgery, with robotics and laser technology, are reviewed and ongoing clinical trials for patients with OPC are discussed.



Swing of the pendulum: Optimizing functional outcomes in larynx cancer

The continued development and integration of new treatment approaches, including organ preservation surgery, transoral minimally invasive surgery of the head and neck, supracricoid partial laryngectomy, intensity-modulated radiotherapy, and targeted molecular therapies, offer the potential to improve clinical outcomes, function, and quality of life.

Transoral lateral oropharyngectomy for squamous cell carcinoma of the tonsillar region: I. Technique, complications, and functional results.

From a functional standpoint, the TLO is a reliable technique that should be considered for treatment of appropriate squamous cell carcinoma of the tonsil and/or tonsillar fossa and its safety, postoperative management, complications, and functional outcomes are described.

Retropharyngeal lymph node metastases in head and neck malignancies

Through improved diagnostic techniques and heightened awareness of RPLN metastasis, patients at risk of having these metastases can be treated more effectively.

Postoperative Adjuvant Therapy after Transoral Robotic Resection for Oropharyngeal Carcinomas: Rationale and Current Treatment Approach

It is important for all members of the multidisciplinary treatment team to have a clear understanding of the foundation for adjuvant therapy and the issues unique to transoral robotic surgery to provide optimal patient care as this new treatment paradigm gains popularity for its safe application.

Functional and oncologic results following transoral laser microsurgical excision of base of tongue carcinoma

Transoral robotic-assisted surgery for head and neck squamous cell carcinoma: one- and 2-year survival analysis.

Results of Kaplan-Meier survival analysis showed that the 2-year recurrence-free survival rate for the cohort was 86.5%.

Primary surgery as treatment for early squamous cell carcinoma of the tonsil

The management of tonsil carcinoma has gradually evolved such that the literature is replete with outcome summaries of this disease treated with primary RT and chemotherapy. Recently there have been

Transoral laser microsurgery for squamous cell carcinoma of the base of the tongue.

The concept of organ and function preserving laser microsurgery for selected patients with base of tongue cancer seems to be justified considering the achieved oncological and functional results.

Transoral laser microsurgery: applications in head and neck oncology

Guy J Petruzzelli, MD, PhD, FACS Charles Arthur Weaver Professor of Cancer Research; and Professor, Departments of Otolaryngology and Neurosurgery, Rush University Medical Center, 1725 West Harrison,