Transoral laser microsurgery as primary treatment for advanced‐stage oropharyngeal cancer: A united states multicenter study

@article{Haughey2011TransoralLM,
  title={Transoral laser microsurgery as primary treatment for advanced‐stage oropharyngeal cancer: A united states multicenter study},
  author={Bruce H. Haughey and Michael L. Hinni and John R. Salassa and Richard E. Hayden and David G. Grant and Jason T. Rich and Simon Milov and James S. Lewis and Murli Krishna},
  journal={Head \& Neck},
  year={2011},
  volume={33}
}
Nonsurgical modalities are sometimes advocated as the standard of care for advanced oropharyngeal tumors. Oncologic and functional results have been modest. The aim of our study was to evaluate outcomes of a minimally invasive approach, using transoral laser microsurgery (TLM) as the primary treatment for advanced oropharyngeal carcinoma. 

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References

SHOWING 1-10 OF 53 REFERENCES

Transoral laser microsurgery (TLM) ± adjuvant therapy for advanced stage oropharyngeal cancer

Document survival, prognostic variables, and functional outcomes of patients with AJCC stage III or IV oropharyngeal cancer, treated with transoral laser microsurgery (TLM) ± adjuvant therapy.

Carcinoma of the Tongue Base Treated by Transoral Laser Microsurgery, Part One: Untreated Tumors, a Prospective Analysis of Oncologic and Functional Outcomes

Objectives: To report the oncologic and functional outcomes of transoral laser microsurgery (TLM) in the management of untreated primary carcinoma of the tongue base.

Transoral laser microsurgery for advanced laryngeal cancer.

In patients with advanced laryngeal cancer, TLM with or without radiotherapy is a valid treatment strategy for organ preservation and low morbidity and mortality and excellent oncologic and functional outcomes make TLM an attractive therapeutic option.

Adjuvant radiotherapy after transoral laser microsurgery for advanced squamous carcinoma of the head and neck.

Functional Outcomes After Primary Oropharyngeal Cancer Resection and Reconstruction With the Radial Forearm Free Flap

Patients having reconstruction with radial forearm free flaps after primary resection for oropharyngeal cancer are reported on for aeromechanical, acoustical, and perceptual speech outcomes, as well as preliminary swallowing data.

Transoral laser microsurgery for squamous cell carcinoma of the base of the tongue.

The concept of organ and function preserving laser microsurgery for selected patients with base of tongue cancer seems to be justified considering the achieved oncological and functional results.

Intensity‐modulated chemoradiation for treatment of stage III and IV oropharyngeal carcinoma

Treatment outcomes for stage III and IV oropharyngeal carcinoma treated with intensity‐modulated radiotherapy (IMRT) and concurrent chemotherapy without prior surgical resection were reviewed.

The role of salvage surgery in patients with recurrent squamous cell carcinoma of the oropharynx

Overall survival, functional outcomes, and prognostic factors in patients who underwent salvage surgery for locally recurrent squamous cell carcinoma of the oropharynx (SCCOP) after initial radiotherapy are reviewed.

Precisely defining high‐risk operable head and neck tumors based on rtog #85‐03 and #88‐24: Targets for postoperative radiochemotherapy?

Local‐regional recurrence of disease remains the major obstacle to cure of advanced head and neck cancers.
...