Transneuronal degeneration of retinal ganglion cells in early hemispherectomized monkeys.

@article{Herbin1999TransneuronalDO,
  title={Transneuronal degeneration of retinal ganglion cells in early hemispherectomized monkeys.},
  author={Michel Herbin and Denis Boire and Hugo Th{\'e}oret and Maurice Ptito},
  journal={Neuroreport},
  year={1999},
  volume={10 7},
  pages={1447-52}
}
Transneuronal retrograde cell changes in the retina of the primate have been well documented after lesions to striate cortex, but little is known about the effects of hemispherectomy, a surgical procedure used in humans for the treatment of intractable epilepsy. In order to follow the time course of this degenerative process, we examined the retinae of six monkeys who underwent a total hemispherectomy at various postnatal ages with a survival period of 4 years. We demonstrate that transneuronal… CONTINUE READING
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