Transneuronal circuit tracing with neurotropic viruses.

  title={Transneuronal circuit tracing with neurotropic viruses.},
  author={Edward M. Callaway},
  journal={Current opinion in neurobiology},
  volume={18 6},
Because neurotropic viruses naturally traverse neural pathways, they are extremely valuable for elucidating neural circuits. Naturally occurring herpes and rabies viruses have been used for transneuronal circuit tracing for decades. Depending on the type of virus and strain, virus can travel preferentially in the anterograde or the retrograde direction. More recently, genetic modifications have allowed for many improvements. These include: reduced pathogenicity; addition of marker genes… CONTINUE READING
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Howley PM (Eds): Fields Virology, edn 5. Philadelphia

  • DM Knipe
  • 2007
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