Transmural dispersion of myofiber mechanics: implications for electrical heterogeneity in vivo.

@article{Ashikaga2007TransmuralDO,
  title={Transmural dispersion of myofiber mechanics: implications for electrical heterogeneity in vivo.},
  author={Hiroshi Ashikaga and Benjamin A Coppola and B. Hopenfeld and Eric S. Leifer and Elliot R. McVeigh and Jeffrey H. Omens},
  journal={Journal of the American College of Cardiology},
  year={2007},
  volume={49 8},
  pages={909-16}
}
OBJECTIVES We investigated whether transmural mechanics could yield insight into the transmural electrical sequence. BACKGROUND Although the concept of transmural dispersion of repolarization has helped explain a variety of arrhythmias, its presence in vivo is still disputable. METHODS We studied the time course of transmural myofiber mechanics in the anterior left ventricle of normal canines in vivo (n = 14) using transmural bead markers under biplane cineradiography. In 4 of these animals… CONTINUE READING
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