Transmucosal macromolecular drug delivery.

  title={Transmucosal macromolecular drug delivery.},
  author={Cecilia Prego and Marcos Garc{\'i}a and D. Torres and Maria Jose Castro Alonso},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  volume={101 1-3},
Mucosal surfaces are the most common and convenient routes for delivering drugs to the body. However, macromolecular drugs such as peptides and proteins are unable to overcome the mucosal barriers and/or are degraded before reaching the blood stream. Among the approaches explored so far in order to optimize the transport of these macromolecules across mucosal barriers, the use of nanoparticulate carriers represents a challenging but promising strategy. The present paper aims to compare the… CONTINUE READING