Transmitter-receptor mismatch in GABAergic synapses in the absence of activity.

  title={Transmitter-receptor mismatch in GABAergic synapses in the absence of activity.},
  author={Roberta Cesa and Laura Morando and Piergiorgio Strata},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={105 48},
Competition among different axons to reach the somatodendritic region of the target neuron is an important event during development to achieve the final architecture typical of the mature brain. Trasmitter-receptor matching is a critical step for the signaling between neurons. In the cerebellar cortex, there is a persistent competition between the two glutamatergic inputs, the parallel fibers and the climbing fibers, for the innervation of the Purkinje cells. The activity of the latter input is… CONTINUE READING

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