Transmission of bovine spongiform encephalopathy to sheep and goats.

  title={Transmission of bovine spongiform encephalopathy to sheep and goats.},
  author={James D. Foster and James Hope and Hugh Fraser},
  journal={The Veterinary record},
  volume={133 14},
Spongiform encephalopathy has been confirmed in both 'positive' and 'negative' lines of Cheviot sheep (selected for their differential response on experimental exposure to scrapie) after intracerebral injection or oral dosing with brain homogenate derived from cattle with bovine spongiform encephalopathy (BSE). With either challenge the incubation period of the disease ranged from 440 to 994 days in both lines of sheep. In a similar experiment, three Anglo-Nubian goats developed the disease 506… CONTINUE READING