Transmission of SARS-CoV-2 Lineage B.1.1.7 in England: Insights from linking epidemiological and genetic data

@inproceedings{Volz2021TransmissionOS,
  title={Transmission of SARS-CoV-2 Lineage B.1.1.7 in England: Insights from linking epidemiological and genetic data},
  author={Erik M. Volz and Swapnil Mishra and Meera Chand and Jeffrey C. Barrett and Robert Johnson and Lily Geidelberg and Wes Hinsley and Daniel J. Laydon and Gavin Dabrera and {\'A}ine Niamh O'toole and Roberto Amato and Manon Ragonnet-Cronin and Ian Harrison and Ben Jackson and Cristina V. Ariani and Olivia Boyd and Nicholas James Loman and John T. McCrone and S{\'o}nia Gonçalves and David Jorgensen and Richard Myers and Verity Hill and David K Jackson and Katy A. M. Gaythorpe and Natalie Groves and John Sillitoe and Dominic P. Kwiatkowski and Seth Flaxman and Oliver Ratmann and Samir Bhatt and Susan Hopkins and Axel Gandy and Andrew Rambaut and Neil M. Ferguson},
  booktitle={medRxiv},
  year={2021}
}
The SARS-CoV-2 lineage B.1.1.7, now designated Variant of Concern 202012/01 (VOC) by Public Health England, originated in the UK in late Summer to early Autumn 2020. We examine epidemiological evidence for this VOC having a transmission advantage from several perspectives. First, whole genome sequence data collected from community-based diagnostic testing provides an indication of changing prevalence of different genetic variants through time. Phylodynamic modelling additionally indicates that… 
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