Transmission of HIV-1 drug-resistant variants: prevalence and effect on treatment outcome.

@article{Jakobsen2010TransmissionOH,
  title={Transmission of HIV-1 drug-resistant variants: prevalence and effect on treatment outcome.},
  author={Martin Roelsgaard Jakobsen and Martin Tolstrup and Ole Schmeltz S\ogaard and Louise Bruun J\orgensen and Paul R. Gorry and Alex Lund Laursen and Lars Fr\osig Ostergaard},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2010},
  volume={50 4},
  pages={566-73}
}
BACKGROUND Human immunodeficiency virus type 1 (HIV-1) drug resistance is an important threat to the overall success of antiretroviral therapy (ART). Because of the limited sensitivity of commercial assays, transmitted drug resistance (TDR) may be underestimated; thus, the effect that TDR has on treatment outcome needs to be investigated. The objective of… CONTINUE READING