Transmission networks of drug resistance acquired in primary/early stage HIV infection.

@article{Brenner2008TransmissionNO,
  title={Transmission networks of drug resistance acquired in primary/early stage HIV infection.},
  author={Bluma G Brenner and M. Roger and Daniela D Moisi and Maureen Oliveira and I Trotter Hardy and Reuven Turgel and Hugues Charest and Jean-pierre Routy and Mark A. Wainberg},
  journal={AIDS},
  year={2008},
  volume={22 18},
  pages={2509-15}
}
OBJECTIVES Population-based sequencing of primary/recent HIV infections (PHIs) can provide a framework for understanding transmission dynamics of local epidemics. In Quebec, half of PHIs represent clustered transmission events. This study ascertained the cumulative implications of clustering on onward transmission of drug resistance. METHODS HIV-1 pol sequence datasets were available for all genotyped PHI (<6 months postseroconversion; n = 848 subtype B infections, 1997-2007). Phylogenetic… CONTINUE READING

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