Transmission event of SARS-CoV-2 Delta variant reveals multiple vaccine breakthrough infections

@article{Farinholt2021TransmissionEO,
  title={Transmission event of SARS-CoV-2 Delta variant reveals multiple vaccine breakthrough infections},
  author={Timothy Farinholt and Harshavardhan Doddapaneni and Xiang Qin and Vipin Menon and Qingchang Meng and Ginger A Metcalf and Hsu Chao and Marie-Claude Gingras and Paige Farinholt and Charu Agrawal and Donna M. Muzny and Pedro A. Piedra and Richard A. Gibbs and Joseph F Petrosino},
  journal={medRxiv},
  year={2021}
}
Importance: Vaccine breakthrough by an emergent SARS-CoV-2 variant poses a great risk to global public health. Objective: To determine the SARS-CoV-2 variant responsible for 6 cases of vaccine breakthrough. Design: Nasopharyngeal swabs from suspected vaccine breakthrough cases were tested for SARS-CoV-2 by qPCR for Wuhan-Hu1 and Alpha variant. Positive samples were then sequenced by Swift Normalase Amplicon Panels to determine the causal variant. Setting: Transmission event occurred at events… 
Transmission of SARS-CoV-2 Delta Variant Among Vaccinated Healthcare Workers, Vietnam
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Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). SARS-CoV-2 has been spreading worldwide since December 2019,
Epidemiology Features and Effectiveness of Vaccination and Non-Pharmaceutical Interventions of Delta and Lambda SARS-CoV-2 Variants
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The epidemic characteristics and prevention and control measures for Delta and Lambda, and the effect of vaccination on the SARS-CoV-2 virus, especially the current predominant strain of Delta variant, has become the focus of global concern.
Predominance of antibody-resistant SARS-CoV-2 variants in vaccine breakthrough cases from the San Francisco Bay Area, California
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It is suggested that vaccine breakthrough cases are preferentially caused by circulating antibody-resistant SARS-CoV-2 variants, and that symptomatic breakthrough infections may potentially transmit COVID-19 as efficiently as unvaccinated infections, regardless of the infecting lineage.
Effect of Vaccination on Household Transmission of SARS-CoV-2 Delta VOC
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The results imply that vaccinations reduce susceptibility as well as transmissibility and that unvaccinated individuals with an infection exhibited a higher viral load compared to fully vaccinated individuals with a breakthrough infection.
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