Transmission disequilibrium testing of arginine vasopressin receptor 1A (AVPR1A) polymorphisms in autism

@article{Kim2002TransmissionDT,
  title={Transmission disequilibrium testing of arginine vasopressin receptor 1A (AVPR1A) polymorphisms in autism},
  author={Sung-jin Kim and Larry E. Young and David Gonen and Jeremy Veenstra-VanderWeele and Rachel Y Courchesne and Eric Courchesne and C. Lord and Bennett L. Leventhal and E H Cook and Thomas R. Insel},
  journal={Molecular Psychiatry},
  year={2002},
  volume={7},
  pages={503-507}
}
Impairment in social reciprocity is a central component of autism. In preclinical studies, arginine vasopressin (AVP) has been shown to increase a range of social behaviors, including affiliation and attachment, via the V1a receptor (AVPR1A) in the brain. Both the behavioral effects of AVP and the neural distribution of the V1a receptor vary greatly across… CONTINUE READING