Transmission and passage of experimenal "kuru" to chimpanzees.

@article{Gajdusek1967TransmissionAP,
  title={Transmission and passage of experimenal "kuru" to chimpanzees.},
  author={D. Carleton Gajdusek and Clarence J. Gibbs and Michael P. Alpers},
  journal={Science},
  year={1967},
  volume={155 3759},
  pages={
          212-4
        }
}
Kuru, a familial degenerative disease of the nervous system occurring in a restricted area of the Highlands of New Guinea, has apparently been transmitted to chimpanzees, but not to any other of the many experimental hosts tried. Transmission of the kuru syndrome from chimpanzee to chimpanzee has now been effected, with a shortening of the incubation period to 1 year from the 1 1/2 to 2 1/2 years found on intracerebral passage of human brain tissue to chimpanzee. Other chimpanzees have been… 

TRANSMISSION EXPERIMENTS WITH KURU IN CHIMPANZEES AND THE ISOLATION OF LATENT VIRUSES FROM THE EXPLANTED TISSUES OF AFFECTED ANIMALS

The current status of long-term efforts to isolate the causative agent of kuru from patients or from chimpanzees to which the disease has been experimentally transmitted is reported, with more than 50 virus strains from long-maintained explant cultures of 11 tissues obtained from chimpanzees affected with kuru.

Discussion on kuru, scrapie and the experimental kuru-like syndrome in chimpanzees.

  • C. Gajdusek
  • Medicine
    Current topics in microbiology and immunology
  • 1967
The first successful transmission of a subacute or chronic central nervous system degeneration of man to primate that has excited the imagination and raised the hopes that otherSubacute and chronic degenerative nervous system disorders may also be transmissible.

Transmission of Experimental Kuru to the Spider Monkey (Ateles geoffreyi)

Clinical signs and pathological changes characteristic of kuru in man and experimental kuru in chimpanzees were observed in two spider monkeys, Ateles geoffreyi, after inoculation with brain tissue

Prion Diseases

The discovery of kuru opened new windows into the realms of human medicine, and was instrumental in the later transmission of Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker disease, as well as the relevance that bovine spongiform encephalopathy had for transmission to humans.

Kuru: A Journey Back in Time from Papua New Guinea to the Neanderthals’ Extinction

The discovery of kuru opened new windows into the realms of human medicine and was instrumental in the later transmission of Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker disease as well as the relevance that bovine spongiform encephalopathy had for transmission to humans.

Kuru and D. Carleton Gajdusek: a close encounter.

The discovery of kuru opened new windows into the realms of human medicine and was instrumental in the later transmission of Creutzfeldt-Jakob disease as well as the prediction that bovine spongiform encephalopathy would be transmitted to humans.

Transmission of Two Subacute Spongiform Encephalopathies of Man (Kuru and Creutzfeldt–Jakob Disease) to New World Monkeys

Now that kuru and Creutzfeldt–Jakob disease have been transmitted to four species of New World monkeys, spider monkeys, capuchin monkeys, squirrel monkeys, and woolly monkeys, these more readily available animals may replace the chimpanzee in the laboratory study of these two subacute degenerative diseases of the human brain.

Degenerative diseases of the central nervous system transmissible to experimental animals

The clinical features and the pathological changes in the central nervous system of scrapie and kuru are described and attention is drawn to the similarities between these conditions. In both,

Kuru, the First Human Prion Disease †

The discovery of kuru opened new vistas of human medicine and was pivotal in the subsequent transmission of Creutzfeldt–Jakob disease, as well as the relevance that bovine spongiform encephalopathy had for transmission to humans.
...

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