Transmembrane Protein 55B Is a Novel Regulator of Cellular Cholesterol Metabolism

@article{Medina2014TransmembraneP5,
  title={Transmembrane Protein 55B Is a Novel Regulator of Cellular Cholesterol Metabolism},
  author={M. Medina and F. Bauzon and Devesh Naidoo and E. Theusch and Kristen Stevens and Jessica Schilde and C. Schubert and L. Mangravite and L. Rudel and R. Temel and H. Runz and R. Krauss},
  journal={Arteriosclerosis, Thrombosis, and Vascular Biology},
  year={2014},
  volume={34},
  pages={1917–1923}
}
  • M. Medina, F. Bauzon, +9 authors R. Krauss
  • Published 2014
  • Medicine, Biology
  • Arteriosclerosis, Thrombosis, and Vascular Biology
  • Objective— Interindividual variation in pathways affecting cellular cholesterol metabolism can influence levels of plasma cholesterol, a well-established risk factor for cardiovascular disease. Inherent variation among immortalized lymphoblastoid cell lines from different donors can be leveraged to discover novel genes that modulate cellular cholesterol metabolism. The objective of this study was to identify novel genes that regulate cholesterol metabolism by testing for evidence of correlated… CONTINUE READING
    11 Citations
    SUGP1 is a novel regulator of cholesterol metabolism
    • 15
    • PDF
    RP1-13D10.2 Is a Novel Modulator of Statin-Induced Changes in Cholesterol
    • 15
    • PDF
    TMEM55B contributes to lysosomal homeostasis and amino acid–induced mTORC1 activation
    • 5
    Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation
    Chronic Cigarette Smoke Mediated Global Changes in Lung Mucoepidermoid Cells: A Phosphoproteomic Analysis.
    • 13
    Phosphorylation of TMEM55B by Erk/MAPK regulates lysosomal positioning.
    • 3
    Neural-specific distribution of transmembrane protein TMEM240 and formation of TMEM240-Body.

    References

    SHOWING 1-10 OF 36 REFERENCES
    RHOA Is a Modulator of the Cholesterol-Lowering Effects of Statin
    • 27
    • PDF
    Identification of cholesterol-regulating genes by targeted RNAi screening.
    • 129
    Differential Gene Expression of Blood-Derived Cell Lines in Familial Combined Hyperlipidemia
    • 26
    Combined Influence of LDLR and HMGCR Sequence Variation on Lipid-Lowering Response to Simvastatin
    • 64
    • PDF