Transmembrane Protein 55B Is a Novel Regulator of Cellular Cholesterol Metabolism

  title={Transmembrane Protein 55B Is a Novel Regulator of Cellular Cholesterol Metabolism},
  author={M. Medina and F. Bauzon and Devesh Naidoo and E. Theusch and Kristen Stevens and Jessica Schilde and C. Schubert and L. Mangravite and L. Rudel and R. Temel and H. Runz and R. Krauss},
  journal={Arteriosclerosis, Thrombosis, and Vascular Biology},
  • M. Medina, F. Bauzon, +9 authors R. Krauss
  • Published 2014
  • Medicine, Biology
  • Arteriosclerosis, Thrombosis, and Vascular Biology
  • Objective— Interindividual variation in pathways affecting cellular cholesterol metabolism can influence levels of plasma cholesterol, a well-established risk factor for cardiovascular disease. Inherent variation among immortalized lymphoblastoid cell lines from different donors can be leveraged to discover novel genes that modulate cellular cholesterol metabolism. The objective of this study was to identify novel genes that regulate cholesterol metabolism by testing for evidence of correlated… CONTINUE READING
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