Transmantle dysplasia in tuberous sclerosis: clinical features and surgical outcome in four children.

@article{Vigliano2002TransmantleDI,
  title={Transmantle dysplasia in tuberous sclerosis: clinical features and surgical outcome in four children.},
  author={Piernanda Vigliano and Carlotta Canavese and Barbara Bobba and Lorenzo Genitori and Francesco Papalia and Sergio Padovan and Marco Forni},
  journal={Journal of child neurology},
  year={2002},
  volume={17 10},
  pages={752-8}
}
In the literature, several malformations of cortical development have been described as additional lesions in tuberous sclerosis complex. Among these lesions, a very large focal cortical dysplasia has peculiar magnetic resonance imaging features: a signal abnormality that extends radially inward toward the lateral ventricle from the pachygyric cortical surface plus a homogeneous clinical picture. Affected patients have early-onset drug-resistant epilepsy and severe developmental delay. We… CONTINUE READING

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