Translocation renal cell carcinomas in adults: a single-institution experience.

  title={Translocation renal cell carcinomas in adults: a single-institution experience.},
  author={Minghao Zhong and Patricia De Angelo and Lisa Osborne and Alberto Enrique Paniz-Mondolfi and Matthew Geller and Youfeng Yang and W. Marston Linehan and Mar{\'i}a Jos{\'e} Beato Merino and Carlos Cordon-Cardo and Dongming Cai},
  journal={The American journal of surgical pathology},
  volume={36 5},
Translocation renal cell carcinoma is a newly recognized subtype of renal cell carcinoma (RCC) with chromosomal translocations involving TFE3 (Xp11.2) or, less frequently, TFEB (6p21). Xp11 translocation RCC was originally described as a pediatric neoplasm representing 20% to 40% of pediatric RCCs, with a much lower frequency in the adult population. TFEB translocation RCC is very rare, with approximately 10 cases reported in the literature. Here, we describe the clinicopathologic features of… CONTINUE READING