Translocation joins c-myc and immunoglobulin γ1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene

Abstract

Recombinant DNA clones have been used to directly demonstrate that the Burkitt lymphoma cell line Raji, t(8;14) (q24;q32), has a rearranged copy of the c-myc gene adjacent to the γ1 constant region gene of the human immunoglobulin heavy-chain locus ; the genes are arranged in the opposite direction for transcription. At least one further 5′ exon has been… (More)
DOI: 10.1038/304135a0

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