Translesion and Repair DNA Polymerases: Diverse Structure and Mechanism.

Abstract

The number of DNA polymerases identified in each organism has mushroomed in last two decades. Most newly found DNA polymerases specialize in translesion synthesis and DNA repair instead of replication. Although intrinsic error rates are higher for translesion and repair polymerases than for replicative polymerases, the specialized polymerases increase… (More)
DOI: 10.1146/annurev-biochem-062917-012405

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