Translational studies on acute myeloid leukemia focus on the receptor tyrosine kinase FLT3

@inproceedings{Marhll2018TranslationalSO,
  title={Translational studies on acute myeloid leukemia focus on the receptor tyrosine kinase FLT3},
  author={Alissa Marh{\"a}ll},
  year={2018}
}
Among adults, acute myeloid leukemia (AML) is the second most frequent type of leukemia. In spite of recent improvements in the treatment of this disease, a majority of patients develop drug resistance, leading to poor overall survival. One of the factors behind this is mutations in the tyrosine kinase receptor (FLT3). It is one of the most commonly mutated genes and is present in almost 40% of the patients with AML. In order to deal with the resistance and improve current treatments, a better… CONTINUE READING

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