Translational research: Crossing the valley of death
@article{Butler2008TranslationalRC, title={Translational research: Crossing the valley of death}, author={Declan Butler}, journal={Nature}, year={2008}, volume={453}, pages={840-842} }
A chasm has opened up between biomedical researchers and the patients who need their discoveries. Declan Butler asks how the ground shifted and whether the US National Institutes of Health can bridge the gap.
535 Citations
Academic leadership: (with)holding the keys to translational medicine?
- MedicineNature medicine
- 2019
To promote effective translational medicine, academia must take the lead in creating a conducive environment for the first steps into translation, urge Roch Ogier and colleagues.
Introduction: What Is Translational Research
- Medicine
- 2015
A very practical and short definition of Translational Research could be the application of findings from Basic Research to patient, community and population care and to the advancement of the delivery of health services.
Are Academic Medical Centers Placing Translational Scientists on the Endangered Species List?
- MedicineJACC. Basic to translational science
- 2017
Academic, Foundation, and Industry Collaboration in Finding New Therapies
- MedicineThe New England journal of medicine
- 2017
A growing approach to developing new treatments is a partnership among researchers, patient groups, and industry, and three examples of such collaborations are given.
Imaging and the Valley of Death: Developing the Evidence Base for the Use of Imaging in Follow-Up.
- MedicineJACC. Cardiovascular imaging
- 2016
TraIT, Translational research IT bridging the valley of death in translational medicine
- Computer Science, MedicinebioRxiv
- 2020
The Dutch Translational research IT (TraIT) initiative organizes, deploys, and manages data and workflows in an on-line “office suite”, supplemented with efficient training and user support.
Next-generation academic medicine.
- Medicine, EducationThe Journal of clinical investigation
- 2012
Today I would like to speak to you about the remarkable successes of academic medical centers to date, the significant problems that we are now facing, and the need for us to evolve into the next…
Close to the bench as well as at the bedside: involving service users in all phases of translational research
- Chemistry, MedicineHealth expectations : an international journal of public participation in health care and health policy
- 2012
This paper aims to develop a model of translational research in which service user and other stakeholder involvement are central to each phase of the research process.
The challenges of modern interdisciplinary medical research
- MedicineNature Biotechnology
- 2011
The increasing complexity of medical science poses significant challenges to medical education, leading to a growing gap between medical researchers and treating practitioners.