Translational repression of brlA expression prevents premature development in Aspergillus.

  title={Translational repression of brlA expression prevents premature development in Aspergillus.},
  author={Sun-ho Han and Jean Navarro and Ralf Greve and Thomas H. Adams},
  journal={The EMBO journal},
  volume={12 6},
The Aspergillus nidulans brlA developmental regulatory locus consists of two overlapping transcription units, brlA alpha and brlA beta, which encode functionally related polypeptides. We used translational fusions between each of the predicted brlA reading frames and the Escherichia coli lacZ gene to test the hypothesis that developmental regulation of brlA alpha and brlA beta expression occurs through different mechanisms. brlA alpha is transcriptionally controlled and a large portion of brlA… CONTINUE READING


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