Translational repression determines a neuronal potential in Drosophila asymmetric cell division

@article{Okabe2001TranslationalRD,
  title={Translational repression determines a neuronal potential in Drosophila asymmetric cell division},
  author={Masataka Okabe and Takao Imai and Mitsuhiko Kurusu and Yasushi Hiromi and Hideyuki Okano},
  journal={Nature},
  year={2001},
  volume={411},
  pages={94-98}
}
Asymmetric cell division is a fundamental strategy for generating cellular diversity during animal development1. Daughter cells manifest asymmetry in their differential gene expression. Transcriptional regulation of this process has been the focus of many studies, whereas cell-type-specific ‘translational’ regulation has been considered to have a more minor role. During sensory organ development in Drosophila, Notch signalling directs the asymmetry between neuronal and non-neuronal lineages2… CONTINUE READING
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